Publications 2013

We have listed only items that contain BBMRI-NL or the grant number in the affiliation, funding and/or acknowledgement section of the article. Items are listed per year in alphabetical order.
  • Abdellaoui A, Hottenga JJ, Xiao XJ, Scheet P, Ehli EA, Davies GE, Hudziak JJ, Smit DJA, Bartels M, Willemsen G, et al.: Association between autozygosity and major depression: Stratification due to religious assortment. Behavior Genetics 43(6): 455-467.
  • Abdellaoui A, Hottenga JJ, de Knijff P, Nivard MG, Xiao XJ, Scheet P, Brooks A, Ehli EA, Hu YS, Davies GE, et al.: Population structure, migration, and diversifying selection in the Netherlands. European Journal of Human Genetics 21(11): 1277-1285.
  • Albrechtsen A, Grarup N, Li Y, Sparso T, Tian G, Cao H, Jiang T, Kim SY, Korneliussen T, Li Q, et al.: Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia 56(2): 298-310.
  • Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, et al.: Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nature Genetics 45(8): 912-917.
  • Bardai A, Amin AS, Blom MT, Bezzina CR, Berdowski J, Langendijk PNJ, Beekman L, Klemens CA, Souverein PC, Koster RW, et al.: Sudden cardiac arrest associated with use of a non-cardiac drug that reduces cardiac excitability: Evidence from bench, bedside, and community. European Heart Journal 34(20): 1506-1516.
  • Bekkers MB, Aalberse RC, Gehring U, Kerkhof M, Koppelman GH, de Jongste JC, Smit HA, Brunekreef B, Wijga AH: Hen's egg, not cow's milk, sensitization in infancy is associated with asthma: 10-year follow-up of the PIAMA birth cohort. Journal of Allergy and Clinical Immunology 132(6): 1427-1428.
  • Berndt SI, Gustafsson S, Magi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, et al.: Genomewide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics 45(5): 501-512.
  • Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJC, et al.: Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. European Journal of Human Genetics 21(10): 1163-1168.
  • Byelas G, Dijkstra M, Neerincx PBT, Van Dijk F, Kanterakis A, Deelen P, Swertz M: Scaling bio-analyses from computational clusters to grids. COER Proceedings 993: no 2.
  • Couch FJ, Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker KB, Soucy P, Fredericksen Z, Barrowdale D, Dennis J, et al.: Genomewide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet 9(3): e1003212.
  • Deelen J, van Dijk F, Francioli L, Hottenga JJ, van Leeuwen EM, Kattenberg M, Karssen LC, Estrada K, Consortium TGotN, Rivadeneira F, et al.: The ‘Genome of the Netherlands’ outperforms ’1000 genomes’ as a reference set for imputing rare variants in the european population. European Society of Human Genetics (2013): 48.
  • Dijkstra JK, Lindenberg S, Zijlstra L, Bouma E, Veenstra R: The secret ingredient for social success of young males: A functional polymorphism in the 5HT(2A) serotonin receptor gene. PLoS One 8(2): e54821.
  • Dongen van J, Willemsen G, Chen WM, de Geus EJC, Boomsma DI: Heritability of metabolic syndrome traits in a large populationbased sample. Journal of Lipid Research 54(10): 2914-2923.
  • Draisma HHM, Beekman M, Pool R, van Ommen GJB, Vaarhorst AAM, de Craen AJM, Willemsen G, Slagboom PE, Boomsma DI: Familial resemblance for serum metabolite concentrations. Twin Research and Human Genetics 16(5): 947-961.
  • Dura P, Bregitha CVV, te Morsche RHM, Roelofs HMJ, Kristinsson JO, Wobbes T, Witteman BJM, Tan AC, Drenth JPH, Peters WHM: Gwasuncovered snps in PLCE1 and RFT2 genes are not implicated in Dutch esophageal adenocarcinoma and squamous cell carcinoma etiology. European Journal of Cancer Prevention 22(5): 417-419.
  • Dura P, Salomon J, te Morsche RHM, Roelofs HMJ, Kristinsson JO, Wobbes T, Witteman BJM, Tan AC, Drenth JPH, Peters WHM: No role for glutathione s-transferase genotypes in caucasian esophageal squamous cell or adenocarcinoma etiology: An european case-control study. BMC Gastroenterology 13: 97.
  • Dura P, van Veen EM, Salomon J, te Morsche RHM, Roelofs HMJ, Kristinsson JO, Wobbes T, Witteman BJM, Tan A, Drenth JPH, et al.: Barrett associated MHC and FOXF1 variants also increase esophageal carcinoma risk. International Journal of Cancer 133(7): 1751-1755.
  • Dura P, Berkers T, van Veen EM, Salomon J, te Morsche RHM, Roelofs HMJ, Kristinsson JO, Wobbes T, Witteman BJM, Tan AC, et al.: Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: A Dutch caucasian case-control study. Journal of Human Genetics 58(11): 742-748.
  • Fall T, Hagg S, Magi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, et al.: The role of adiposity in cardiometabolic traits: A Mendelian randomization analysis. Plos Medicine 10(6): e1001474.
  • Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, et al.: Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics 22(8): 1663-1678.
  • Gaudet MM, Kuchenbaecker KB, Vijai J, Klein RJ, Kirchhoff T, McGuffog L, Barrowdale D, Dunning AM, Lee A, Dennis J, et al.: Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. PLoS Genetics 9(3): e1003173.
  • Gerven van NMF, de Boer YS, Zwiers A, van Hoek B, van Erpecum KJ, Beuers U, van Buuren HR, Drenth JPH, den Ouden JW, Verdonk RC, et al.: Cytotoxic t lymphocyte antigen-4+49a/g polymorphism does not affect susceptibility to autoimmune hepatitis. Liver International 33(7): 1039-1043.
  • Gonzalez-Covarrubias V, Beekman M, Uh HW, Dane A, Troost J, Paliukhovich I, van der Kloet FM, Houwing-Duistermaat J, Vreeken RJ, Hankemeier T, et al.: Lipidomics of familial longevity. Aging Cell 12(3): 426-434.
  • Hafkamp-de Groen E, Lingsma HF, Caudri D, Levie D, Wijga A, Koppelman GH, Duijts L, Jaddoe VW, Smit HA, Kerkhof M, et al.: Predicting asthma in preschool children with asthma-like symptoms: Validating and updating the piama risk score. J Allergy Clin Immunol 132(6): 1303-1310.
  • Hansson MG, van Ommen GJB, Chadwick R, Dillner J: Patients would benefit from simplified ethical review and consent procedure. Lancet Oncol 14(6): 451-453.
  • Harrison SC, Smith AJP, Jones GT, Swerdlow DI, Rampuri R, Bown MJ, Folkersen L, Baas AF, de Borst GJ, Blankensteijn JD, et al.: Interleukin-6 receptor pathways in abdominal aortic aneurysm. European Heart Journal 34(48): 3707-3716.
  • Harrison SC, Zabaneh D, Asselbergs FW, Drenos F, Jones GT, Shah S, Gertow K, Sennblad B, Strawbridge RJ, Gigante B, et al.: A genecentric study of common carotid artery remodelling. Atherosclerosis 226(2): 440-446.
  • Hart 't LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, et al.: The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. Diabetes 62(9): 3275-3281.
  • Hartman CA, Hermanns VW, de Jong PJ, Ormel J: Self- or parent report of (co-occurring) internalizing and externalizing problems, and basal or reactivity measures of hpa-axis functioning: A systematic evaluation of the internalizing-hyperresponsivity versus externalizing-hyporesponsivity HPA-axis hypothesis. Biological Psychology 94(1): 175-184.
  • Hens K, van El CE, Borry P, Cambon-Thomsen A, Cornel MC, Forzano F, Lucassen A, Patch C, Tranebjaerg L, Vermeulen E, et al.: Developing a policy for paediatric biobanks: Principles for good practice. European Journal of Human Genetics 21(1): 2-7.
  • Hoed den M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segre AV, Holm H, Handsaker RE, et al.: Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics 45(6): 621-631.
  • Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, et al.: New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics 45(1): 76-82.
  • Iles MM, Law MH, Stacey SN, Han JL, Fang SY, Pfeiffer R, Harland M, MacGregor S, Taylor JC, Aben KK, et al.: A variant in FTO shows association with melanoma risk not due to bmi. Nature Genetics 45(4): 428-432.e421.
  • Kanterakis A, Ricaño-Ponce I, Gutierrez J, Westra H, Franke L, Wijmenga C, Swertz MA: Identifying additional variants associated to celiac disease by imputation-based gwas. European Society of Human Genetics(2013): 371.
  • Kiezun A, Pulit SL, Francioli LC, van Dijk F, Swertz M, Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJB, Wijmenga C, et al.: Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency. PLoS Genetics 9(2): e1003301.
  • Knevel R, Tsonaka R, le Cessie S, van der Linden MP, Huizinga TW, van der Heijde DM, Houwing-Duistermaat JJ, van der Helm-van Mil AH: Comparison of methodologies for analysing the progression of joint destruction in rheumatoid arthritis. Scand J Rheumatol 42(3): 182- 189.
  • Kretschmer T, Dijkstra JK, Ormel J, Verhulst FC, Veenstra R: Dopamine receptor D4 gene moderates the effect of positive and negative peer experiences on later delinquency: The tracking adolescents' individual lives survey study (TRAILS). Dev Psychopathol 25(4 Pt 1): 1107-1117.
  • Lacko M, Voogd AC, Roelofs HM, te Morsche RH, Oude Ophuis MB, Peters WH, Manni JJ: Combined effect of genetic polymorphisms in phase i and ii biotransformation enzymes on head and neck cancer risk. Head and Neck 35(6): 858-867.
  • Legerstee JS, Verhulst FC, Robbers SC, Ormel J, Oldehinkel AJ, van Oort FV: Gender-specific developmental trajectories of anxiety during adolescence: Determinants and outcomes. The TRAILS study. J Can Acad Child Adolesc Psychiatry 22(1): 26-34.
  • Loos van der MJHM, Rietveld CA, Eklund N, Koellinger PD, Rivadeneira F, Abecasis GR, Ankra-Badu GA, Baumeister SE, Benjamin DJ, Biffar R, et al.: The molecular genetic architecture of self-employment. PLoS One 8(4): e60542.
  • Mill J, Heijmans BT: From promises to practical strategies in epigenetic epidemiology. Nature Reviews Genetics 14(8): 585-594.
  • Minica CC, Dolan CV, Hottenga JJ, Willemsen G, Vink JM, Boomsma DI: The use of imputed sibling genotypes in sibship-based association analysis: On modeling alternatives, power and model misspecification. Behavior Genetics 43(3): 254-266.
  • Motazacker MM, Peter J, Treskes M, Shoulders CC, Kuivenhoven JA, Hovingh GK: Evidence of a polygenic origin of extreme high-density lipoprotein cholesterol levels-brief report. Arteriosclerosis Thrombosis and Vascular Biology 33(7): 1521-1528.
  • Neerincx PBT, van Dijk F, Rengaw T, Francioli LC, de Bakker PIW, Wijmenga C, Swertz MA, The Genome of the Netherlands Consortium: Genome NL variant database; towards a deep genetic encyclopedia of dutch variation. European Society of Human Genetics (2013): 287.
  • Nobile H, Vermeulen E, Thys K, Bergmann MM, Borry P: Why do participants enroll in population biobank studies? A systematic literature review. Expert Rev Mol Diagn 13(1): 35-47.
  • Ouden den HEM, Daw ND, Fernandez G, Elshout JA, Rijpkema M, Hoogman M, Franke B, Cools R: Dissociable effects of dopamine and serotonin on reversal learning. Neuron 80(4): 1090-1100.
  • Papachristou E, Ormel J, Oldehinkel AJ, Kyriakopoulos M, Reinares M, Reichenberg A, Frangou S: Child behavior checklist-mania scale (CBCL-MS): Development and evaluation of a population-based screening scale for bipolar disorder. PLoS One 8(8): e69459.
  • Peyrot WJ, Middeldorp CM, Jansen R, Smit JH, de Geus EJC, Hottenga JJ, Willemsen G, Vink JM, Virding S, Barragan I, et al.: Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample. Journal of Affective Disorders 146(1): 91- 99.
  • Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpelainen TO, Esko T, Magi R, Li S, et al.: Sex-stratified genomewide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genetics 9(6): e1003500.
  • Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, et al.: A megaanalysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry 18(4): 497-511.
  • Rooy de DPC, Zhernakova A, Tsonaka R, Willemze A, Kurreeman BAS, Trynka G, van Toorn L, Toes REM, Huizinga TWJ, HouwingDuistermaat JJ, et al.: A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis. Annals of the Rheumatic Diseases 73(6): 1163- 1169.
  • Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, et al.: Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 128(12): 1310-1324.
  • Schaefer JM, Fetissov SO, Legrand R, Claeyssens S, Hoekstra PJ, Verhulst FC, van Oort FVA: Corticotropin (acth)-reactive immunoglobulins in adolescents in relation to antisocial behavior and stress-induced cortisol response. The TRAILS study. Psychoneuroendocrinology 38(12): 3039-3047.
  • Setten van J, Pulit S, Francioli L, Menelaou A, Deelen P, Karssen L, Slagboom PE, Boomsma DI, van Duijn CM, Wijmenga C, et al.: From GWAS to WGS: A whole-genome association study in 250 trios of the genome of the Netherlands project. European Society of Human Genetics (2013): 389.
  • Stavrakakis N, Roest AM, Verhulst E, Ormel J, de Jonge P, Oldehinkel AJ: Physical activity and onset of depression in adolescents: A prospective study in the general population cohort TRAILS. Journal of Psychiatric Research 47(10): 1304-1308.
  • Sullivan PF, Daly MJ, Ripke S, Lewis CM, Lin DY, Wray NR, Neale B, Levinson DF, Breen G, Byrne EM, et al.: A mega-analysis of genomewide association studies for major depressive disorder. Molecular Psychiatry 18(4): 497-511.
  • Tragante V, Doevendans P, Nathoe HM, van der Graaf Y, Spiering W, Algra A, de Borst GJ, de Bakker PIW, Asselbergs FW, Smart Study Group: The impact of susceptibility loci for coronary artery disease on other vascular domains and recurrence risk. European Heart Journal 34(37): 2896-2904.
  • Velde van der KJ, Dhekne HS, Swertz MA, Sirigu S, Ropars V, Vinke PC, Rengaw T, van den Akker PC, Rings EHHM, Houdusse A, et al.: An overview and online registry of microvillus inclusion disease patients and their MYO5b mutations. Human Mutation 34(12): 1597-1605.
  • Visser L, de Winter AF, Vollebergh WAM, Verhulst FC, Reijneveld SA: The impact of parenting styles on adolescent alcohol use: The TRAILS study. European Addiction Research 19(4): 165-172.
  • Visser L, de Winter AF, Veenstra R, Verhulst FC, Reijneveld SA: Alcohol use and abuse in young adulthood: Do self-control and parents' perceptions of friends during adolescence modify peer influence? The TRAILS study. Addict Behav 38(12): 2841-2846.
  • Warnier MJ, Blom MT, Bardai A, Berdowksi J, Souverein PC, Hoes AW, Rutten FH, de Boer A, Koster RW, de Bruin ML, et al.: Increased risk of sudden cardiac arrest in obstructive pulmonary disease: A casecontrol study. PLoS One 8(6): e65638.
  • Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, et al.: Systematic identification of trans eqtls as putative drivers of known disease associations. Nature Genetics 45(10): 1238-U1195.
  • Willemsen G, Vink JM, Abdellaoui A, den Braber A, van Beek JHDA, Draisma HHM, van Dongen J, van 't Ent D, Geels LM, van Lien R, et al.: The adult Netherlands twin register: Twenty-five years of survey and biological data collection. Twin Research and Human Genetics 16(1): 271-281.
  • Woudstra S, van Tol MJ, Bochdanovits Z, van der Wee NJ, Zitman FG, van Buchem MA, Opmeer EM, Aleman A, Penninx BWJH, Veltman DJ, et al.: Modulatory effects of the piccolo genotype on emotional memory in health and depression. PLoS One 8(4): e61494.
  • Ye K, Beekman M, Lameijer EW, Zhang YJ, Moed MH, van den Akker EB, Deelen J, Houwing-Duistermaat JJ, Kremer D, Anvar SY, et al.: Aging as accelerated accumulation of somatic variants: Wholegenome sequencing of centenarian and middle-aged monozygotic twin pairs. Twin Research and Human Genetics 16(6): 1026-1032.
  • Zuurhout MJL, Vijverberg SJH, Raaijmakers JAM, Koenderman L, Postma DS, Koppelman GH, Maitland-van der Zee AH: ARG16 ADRB2 genotype increases the risk of asthma exacerbation in children with a reported use of long-acting beta(2)-agonists: Results of the pacman cohort. Pharmacogenomics 14(16): 1965-1971.